Of mice, men – and fish: Researchers find parallels in spread of human brain cancer cells in mammals, zebrafish

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Scientists at the Fralin Biomedical Research Institute at VTC have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor – fewer than one in 20 patients survive five years after diagnosis.

“Our hope is that this new work in zebrafish will help researchers efficiently evaluate new, much-needed therapeutics in a pre-clinical animal model to target these aggressive and devastating tumors,” said Harald Sontheimer, formerly a professor at the Fralin Biomedical Research Institute at the time of the study.

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